"The effect of dietary intervention with high content of oleocanthal and oleacin olive oil in patients with early-stage Chronic Lymphocytic Leukaemia (CLL): A pilot randomised trial"
The experimental study was conducted with 22 patients who were diagnosed with early stage Chronic Lymphocytic Leukaemia (CLL) and who were under medical supervision and not receiving any treatment. One of the main objectives was to investigate the hypothesis that the anti-cancer biological effect of olive oil is related to its content of specific phenolic compounds and in particular oleocanthal and oleacin. It is the first time that the scientific community has been able to demonstrate that the oral administration of a daily dose of 25 mg of oleocanthal and oleacin through the consumption of 40 ml of extra virgin olive oil for a period of six months could be beneficial for CLL patients, reducing their white blood cell count, inducing the apoptosis of their cancer cells and improving their metabolism.